How to treat a spider bite at home. In some cases, you can treat spider bites at home. For nonvenomous spider bites, follow these steps: Apply an ice pack on and off the bite for 10 minutes at a time. How to treat a spider bite. If you’re unlucky enough to get a spider bite, there are a few things you can do to treat it at home if you suspect a relatively harmless spider was the offender. 1. How to administer first aid for a spider bite. Most spider bites cause only minor injury. A few spiders can be dangerous. This is how to treat a spider bite at home once you’ve eliminated the possibility of the bite being more dangerous than just your common annoyance. 2. Cleanse the wound of the spider bite with warm water. You can also use a bit of soap if you don’t mind the potential sting (especially if you soap contains perfume and other known irritants). How to Treat a Spider Bite at Home Naturally Medically reviewed by Vincent J. Tavella, MPH — Written by Jennifer Leavitt, MS — Updated on February 28, 2020 At-home treatment Diagnosis. Your doctor may suspect a spider bite based on your history and your signs and symptoms. The process might involve talking to someone who saw the bite, having an expert identify the spider and ruling out other possible causes of the symptoms. How to Treat Spider Bites. Spider bites can be itchy and painful. Some bites are serious, but most can be easily treated. While it's helpful to identify the spider bite, you should always seek immediate medical care, because it's pretty. How to treat a spider bite at home. Normally, you wouldn't need medical attention for a spider bite, as the dangerous bites described above are extremely rare. Most of the time, you can use these basic measures to treat a spider bite at home, on your own: A topical antibiotic to help prevent infection. A spider bite can be painful and scary even, but follow through with the home remedies for how to treat a spider bite to heal the infection in no time. If in any case, the pain and infection persist, then consult a physician immediately.